Vildagliptin dihydrate
Vildagliptin dihydrate(Vildagliptin dihydrate)
CAS: 2133364-01-7
化学式: C17H27N3O3
| 中文名 | Vildagliptin dihydrate |
| 英文名 | Vildagliptin dihydrate |
| 别名 | 维达列汀二水合物 维格列汀二水合物 |
| 英文别名 | 2133364-01-7 Vildagliptin dihydrate |
| CAS | 2133364-01-7 |
| 化学式 | C17H27N3O3 |
| 分子量 | 321.42 |
| 存储条件 | 2-8℃ |
| 体外研究 | Vildagliptin promotes beta cell survival by inhibiting cell apoptosis. Vildagliptin also promotes cell proliferation. |
| 体内研究 | Vildagliptin (35 mg/kg; once daily by oral gavage) increases plasma active GLP-1 levels in islets of db/db mice. Vildagliptin (10 µmol/kg; orally) significantly decreases glucose excursions and stimulate insulin secretion in obese male Zucker rats. Animal Model: Male db/db mice (BKS) and wildtype mice Dosage: 35 mg/kg Administration: Oral gavage; once daily; for 6 weeks Result: Increased plasma active GLP-1 levels (22.63±1.19 vs. 11.69±0.44). Animal Model: Obese male Zucker rats Dosage: 10 µmol/kg (Pharmacokinetic Analysis) Administration: Orally Result: Significantly decreased glucose excursions and stimulate insulin secretion. |
供应商列表
现货供应
产品名: Vildagliptin dihydrate 去供应商网站查看 询盘CAS: 2133364-01-7
产地: 上海
规格: V880472
价格: 50mg-1287,10mg-516
库存: 15天内发货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2885703204/288570320
微信: 19863730987/17821173903
现货供应
产品名: Vildagliptin dihydrate 去供应商网站查看 询盘CAS: 2133364-01-7
产地: 上海
规格: V880472
价格: 50mg-1287,10mg-516
库存: 15天内发货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2885703204/288570320
微信: 19863730987/17821173903
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